Amlosun 5 mg (Tablet)
Unit Price: ৳ 5.02 (5 x 10: ৳ 251.00)
Strip Price: ৳ 50.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Sun pharmaceutical bangladesh ltd |
Title & Category
- Amlosun: Amlodipine Medicine
- Hypertension & Angina Treatment
- Calcium-channel Blocker
Indications
- Treats essential hypertension
- Treats chronic stable angina pectoris
- Treats vasospastic angina
Mode of Action
- Dihydropyridine calcium-channel blocker
- Vasodilation effect
- Reduces peripheral resistance
- Increases coronary blood flow
- Increases myocardial oxygen supply
Dosage & Administration
- Usual dose: 5 mg once daily for hypertension
- Maximum dose: 10 mg once daily for hypertension
- Lower dose for elderly and hepatic insufficiency
- 5 to 10 mg for chronic stable or vasospastic angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration with Warfarin
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Benefit vs. risk assessment
- Discontinue nursing during administration
Precautions & Warnings
- Hepatic impairment caution
- Pregnancy and breastfeeding precautions
Use in Special Populations
- Dosage for children with hypertension
- No data for children under 6 years old
- Normal dosage for elderly
- Normal dosage for renal impairment
- Caution and slow titration for severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked systemic hypotension
- Shock with fatal outcome reported
- Active cardiovascular support needed
- Attention to circulating fluid volume
- Vasoconstrictor and calcium gluconate use
- Gastric lavage and charcoal use
- Dialysis not likely to be beneficial
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in cool & dry place
- Protected from light