Demox 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 44.00

Medicine Details

Indications

  • Ear, nose and throat infections
  • Lower respiratory tract infections
  • Skin and soft tissue infections
  • Genito-urinary tract infections
  • Venereal disease
  • Dental abscess therapy
  • H. pylori infection treatment

Pharmacology

  • Broad spectrum penicillin
  • Inhibition of cell wall biosynthesis
  • Stable in the presence of gastric acid
  • Rapid absorption after oral administration

Dosage

  • Adult dosage: 250mg three times daily
  • Children dosage: 125mg three times daily
  • Severe or recurrent purulent respiratory infection: 3g every 12 hours
  • Otitis media: 1g three times daily for adults, 40mg/kg body weight daily in 3 divided doses for children
  • Pneumonia: 500-1000mg three times daily
  • Dental abscess: 3g, repeated after 10-12 hours
  • Urinary tract infections: 3g, repeated after 10-12 hours
  • Gonorrhoea: Single dose of 2-3g with Probenecid 1g
  • Dosage adjustments in renal impairment

Administration

  • Reconstituted suspension can be administered by adding it to milk, fruit juice, or water

Interaction

  • Concurrent use of Demox and Probenecid may result in increased and prolonged blood levels of Demox
  • May affect gut flora and lower estrogen reabsorption

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Mild and transient side effects
  • Diarrhoea
  • Indigestion
  • Rash
  • Rare reports of pseudo-membranous colitis

Pregnancy & Lactation

  • US FDA pregnancy category B
  • Excreted in human milk
  • Caution in lactating mothers

Precautions & Warnings

  • Possibility of superinfections with mycotic or bacterial pathogens
  • Discontinue if superinfections occur

Therapeutic Class

Broad spectrum penicillins

Reconstitution

  • Intramuscular: Add 2.5ml water for injection to Amoxycillin 500mg injection vial
  • Intravenous: Dissolve Amoxycillin 500mg injection in 10ml water for injection

Storage Conditions

Keep in a dry place away from light and heat, Keep out of the reach of children

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