Demoxil 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 70.00

Medicine Details

Indications

  • Ear, nose, and throat infections
  • Lower respiratory tract infections
  • Skin and soft tissue infections
  • Genito-urinary tract infections
  • Venereal disease
  • Dental abscess
  • H. pylori infection and duodenal ulcer
  • Pharyngitis
  • Laryngitis
  • Pneumonia
  • Bronchitis
  • Lung abscess
  • Empyema
  • Bronchiectasis
  • Cellulitis
  • Carbuncles
  • Furunculosis
  • Pyelonephritis
  • Cystitis
  • Urethritis

Pharmacology

  • Broad spectrum penicillin
  • Effective against Gram-positive and Gram-negative bacteria
  • Inhibition of cell wall biosynthesis
  • Stable in the presence of gastric acid
  • Rapidly absorbed after oral administration
  • Widely distributed in body tissues and fluids

Dosage

  • Adult dosage: 250 mg three times daily
  • Higher dosage for severe infections
  • Children dosage: 125 mg three times daily
  • Higher dosage for severe infections in children
  • Specific dosage for respiratory infections, otitis media, pneumonia, dental abscess, urinary tract infections, gonorrhoea
  • Dosage adjustment required in renal impairment

Administration

  • Reconstituted suspension can be administered with milk, fruit juice, water
  • Immediate consumption of prepared suspension

Interaction

  • Increased and prolonged blood levels when used with Probenecid
  • Impact on gut flora and estrogen reabsorption when used with combined oral contraceptives

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Mild and transient side effects
  • Diarrhoea
  • Indigestion
  • Rash
  • Rare cases of pseudo-membranous colitis

Pregnancy & Lactation

  • US FDA pregnancy category B
  • Caution in use during pregnancy if clearly needed
  • Excretion in human milk
  • Caution in use during lactation

Precautions & Warnings

  • Potential for superinfections with mycotic or bacterial pathogens
  • Therapy discontinuation and appropriate therapy for superinfections

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • Specific reconstitution instructions for intramuscular and intravenous administration

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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