E-mox 250 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Edruc limited |
| Also available as |
Title
- E-mox
Categories
- Medicine
- Antibiotic
- Pharmaceutical
Description
E-mox is a broad spectrum penicillin indicated in the treatment of infections due to susceptible beta-lactamase negative strains of microorganisms. It is effective against a wide range of infections including ear, nose, and throat infections, lower respiratory tract infections, skin and soft tissue infections, genito-urinary tract infections, venereal disease, dental abscess, and H. pylori infection.
Color Options
- White
Dosage Form
Tablet, Suspension, Injection
Sizes Available
- 250mg
- 500mg
Pharmacology
Amoxicillin is a broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative bacteria. It acts through the inhibition of biosynthesis of cell wall and is rapidly absorbed after oral administration.
Dosage
- Adult:
- 250 mg three times daily
- 500 mg three times daily for severe infections
- Children:
- 125 mg three times daily
- 250 mg three times daily for severe infections
- Specific Conditions:
- Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
- Otitis media: Recommended dose is 1 g three times daily for adult and 40 mg/kg body weight daily in 3 divided doses for children (max. 3 g daily)
- Pneumonia: Recommended dose is 500-1000 mg three times daily
- Renal Impairment: May require reduction of the total daily dosage.
Administration
Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, or water. These preparations should then be taken immediately.
Interactions
- Concurrent use of E-mox and Probenecid may result in increased and prolonged blood levels of E-mox.
- E-mox may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.
Contraindications
- Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side Effects
- Mild and transient in nature
- May include diarrhoea, indigestion, rash
- Pseudo-membranous colitis reported rarely
Pregnancy and Lactation
- US FDA pregnancy category of Amoxicillin is B
- Should be used during pregnancy only if clearly needed
- Caution should be exercised when administered to a lactating mother
Precautions
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, E-mox should be discontinued and appropriate therapy should be instituted.
Therapeutic Class
- Broad spectrum penicillins
Reconstitution
Amoxycillin 500 mg Injection: Intramuscular - Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial. Intravenous - Dissolve Amoxycillin 500 mg injection in 10 ml water for injection.
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.