E-mox 125 mg/5 ml (Powder for Suspension)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Edruc limited |
| Also available as |
Title
E-mox
Categories
- Antibiotics
- Medications
- Pharmaceuticals
Description
E-mox is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. It is effective against a wide range of Gram-positive and Gram-negative bacteria. The dosage for adults is 250 mg three times daily, increasing up to 500 mg three times daily for severe infections. For children up to 10 years of age, the dosage is 125 mg three times daily, increasing up to 250 mg three times daily for severe infections.
Indications
- Ear, nose and throat infections
- Lower respiratory tract infections
- Skin and soft tissue infections
- Genito-urinary tract infections
- Venereal disease
- Dental abscess
- H. pylori infection and duodenal ulcer disease
Pharmacology
Amoxicillin is a broad spectrum penicillin. It acts through the inhibition of biosynthesis of cell wall. Amoxicillin is stable in the presence of gastric acid and is rapidly absorbed after oral administration. After an oral dose, peak plasma concentration of Amoxicillin is reached within 1 to 2 hours. Amoxicillin is widely distributed at varying concentration in body tissues and fluids.
Dosage
- Adult:
- 250 mg three times daily
- 500 mg three times daily for severe infections
- Children:
- 125 mg three times daily
- 250 mg three times daily for severe infections
Administration
Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, or water. These preparations should then be taken immediately.
Interaction
Concurrent use of E-mox and Probenecid may result in increased and prolonged blood levels of E-mox. E-mox may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side effects
- Diarrhoea
- Indigestion
- Rash
- Pseudo-membranous colitis
Pregnancy and lactation
US FDA pregnancy category of Amoxicillin is B. Caution should be exercised when Amoxicillin is administered to a lactating mother.
Precautions and warnings
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, E-mox should be discontinued and appropriate therapy should be instituted.
Therapeutic class
Broad spectrum penicillins
Reconstitution
- Intramuscular: Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial.
- Intravenous: Dissolve Amoxycillin 500 mg injection in 10 ml water for injection.
Storage conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.