Genamox 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 47.45

Medicine Details

Category Details
Generic Amoxicillin trihydrate
Company General pharmaceuticals ltd
Also available as
Genamox 250 mg capsule Genamox 500 mg capsule Genamox 125 mg pediatric drop

Title

Genamox

Categories

  • Medicine
  • Pharmaceutical

Description

Genamox is a broad spectrum penicillin indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. It is effective against a wide range of Gram-positive and Gram-negative bacteria and is stable in the presence of gastric acid.

Indications

  • Ear, nose and throat infections
  • Lower respiratory tract infections
  • Skin and soft tissue infections
  • Genito-urinary tract infections
  • Venereal disease
  • Dental abscess
  • H. pylori infection and duodenal ulcer disease

Pharmacology

Amoxicillin acts through the inhibition of biosynthesis of cell wall and is rapidly absorbed after oral administration, reaching peak plasma concentration within 1 to 2 hours.

Dosage

  • Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
  • Children: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
  • Special Cases:
    • Severe or recurrent purulent respiratory infection
    • Otitis media
    • Pneumonia
    • Dental abscess
    • Urinary tract infections
    • Gonorrhoea
    • Renal impairment

Administration

Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, or water and should then be taken immediately.

Interaction

  • Concurrent use of Genamox and Probenecid may result in increased and prolonged blood levels of Genamox
  • May affect the gut flora leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives

Contraindications

  • Penicillin hypersensitive patients

Side Effects

  • Mild and transient in nature
  • Diarrhoea
  • Indigestion
  • Rash
  • Pseudo-membranous colitis reported rarely

Pregnancy & Lactation

  • US FDA pregnancy category B
  • Caution should be exercised when administered to lactating mothers

Precautions & Warnings

The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy

Therapeutic Class

Broad spectrum penicillins

Reconstitution

Intramuscular: Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial. Intravenous: Dissolve Amoxycillin 500 mg injection in 10 ml water for injection

Storage Conditions

Keep in a dry place away from light and heat, and out of the reach of children

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