Hi-mox 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 45.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Hudson pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections due to susceptible ß-lactamase negative strains of microorganisms
- Ear, nose, and throat infections (i.e. otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis)
- Lower respiratory tract infections (i.e. pneumonia, acute and chronic bronchitis, lung abscess, empyema, bronchiectasis)
- Skin and soft tissue infections (i.e. cellulitis, carbuncles, furunculosis, infected wounds, abscess)
- Genitourinary tract infections (i.e. pyelonephritis, cystitis, and urethritis)
- Venereal disease (i.e. acute uncomplicated gonorrhea)
- Use in dental abscess as short-term therapy
- Combination therapy for H. pylori infection and duodenal ulcer disease
- Reduction of the risk of duodenal ulcer recurrence
Pharmacology
- Broad spectrum penicillin
- Effective against a wide range of Gram-positive and Gram-negative bacteria
- Inhibition of biosynthesis of cell wall
- Stable in the presence of gastric acid
- Rapid absorption after oral administration
- Widely distributed at varying concentrations in body tissues and fluids
Dosage
- Adult dose: 250 mg three times daily (increasing up to 500 mg three times daily for severe infections)
- Children's dose (up to 10 years of age): 125 mg three times daily (increasing up to 250 mg three times daily for severe infections)
- Specific doses for severe or recurrent purulent respiratory infection, otitis media, pneumonia, dental abscess, urinary tract infections, and gonorrhea
- Dose adjustments in renal impairment
Administration
- Reconstituted suspension can be administered by adding it to milk, fruit juice, or water
- Immediate consumption after preparation
Interaction
- Concurrent use with Probenecid may result in increased and prolonged blood levels
- May affect gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral contraceptives
Contraindications
- Contraindicated in penicillin hypersensitive patients
Side Effects
- Mild and transient nature
- May include diarrhea, indigestion, or occasional rash
- Rare reports of pseudo-membranous colitis
Pregnancy & Lactation
- US FDA pregnancy category of B
- Caution should be exercised when administered to a lactating mother
Precautions & Warnings
- Possibility of superinfections with mycotic or bacterial pathogens
- Need for discontinuation and appropriate therapy if superinfections occur
Therapeutic Class
- Broad spectrum penicillins
Reconstitution
- Specific instructions for reconstituting Amoxycillin 500 mg Injection for intramuscular and intravenous routes
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children