Kamoxy 125 mg/5 ml (Powder for Suspension)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Kemiko pharmaceuticals ltd |
| Also available as |
Indications
- Ear, nose and throat infections (i.e. otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis)
- Lower respiratory tract infections (i.e. pneumonia, acute and chronic bronchitis, lung abscess, empyema, bronchiectasis)
- Skin and soft tissue infections (i.e. cellulitis, carbuncles, furunculosis, infected wounds, abscess)
- Genito-urinary tract infections (i.e. pyelonephritis, cystitis and urethritis)
- Venereal disease (i.e. acute uncomplicated gonorrhoea)
- Dental abscess (short-term therapy)
- Combination therapy for H. pylori infection and duodenal ulcer disease
- Risk reduction of duodenal ulcer recurrence
Pharmacology
Broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative bacteria. Acts through the inhibition of cell wall biosynthesis. Stable in the presence of gastric acid and rapidly absorbed after oral administration.
Dosage
- Adult: 250 mg three times daily, up to 500 mg three times daily for severe infections
- Children: 125 mg three times daily, up to 250 mg three times daily for severe infections
- Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
- Otitis media (adult): 1 g three times daily
- Otitis media (children): 40 mg/kg body weight daily in 3 divided doses (max. 3 g daily)
- Pneumonia: 500-1000 mg three times daily
- Dental abscess: 3 gm, repeated after 10-12 hours
- Urinary tract infections: 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm (Probenecid contraindicated in children under 2 years)
- Renal impairment: May require reduction of total daily dosage
Administration
Reconstituted suspension can be administered by adding to milk, fruit juice, or water, and should then be taken immediately.
Interaction
Concurrent use of Kamoxy and Probenecid may increase and prolong blood levels of Kamoxy. Kamoxy may affect gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side Effects
- Diarrhoea
- Indigestion
- Rash
- Pseudo-membranous colitis (rare)
Pregnancy & Lactation
US FDA pregnancy category B. Caution should be exercised during lactation.
Precautions & Warnings
Consider the possibility of superinfections with mycotic or bacterial pathogens during therapy. If superinfections occur, Kamoxy should be discontinued and appropriate therapy instituted.
Therapeutic Class
Broad spectrum penicillins
Reconstitution
- Amoxycillin 500 mg Injection (Intramuscular): Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial
- Amoxycillin 500 mg Injection (Intravenous): Dissolve in 10 ml water for injection
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.