Loxyl 500 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Asiatic laboratories ltd |
Title
Loxyl
Categories
- Medicine
- Antibiotic
- Pharmaceutical
Description
Loxyl is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. It is a broad spectrum penicillin effective against a wide range of bacteria. It is stable in the presence of gastric acid and is rapidly absorbed after oral administration. The drug is contraindicated in penicillin hypersensitive patients and should be used with caution during pregnancy and lactation. The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy.
Dimensions
N/A
Color options
N/A
Functions
- Treatment of infections
- Inhibition of cell wall biosynthesis
Materials
N/A
Technical specifications
- Adult dosage:
- 250 mg three times daily
- Up to 500 mg three times daily for severe infections
- Children dosage:
- 125 mg three times daily
- Up to 250 mg three times daily for severe infections
- Recommended doses:
- Severe purulent respiratory infection: 3 gm every 12 hours
- Otitis media adult: 1 g three times daily
- Otitis media children: 40 mg/kg body weight daily in 3 divided doses (max. 3 g daily)
- Pneumonia: 500-1000 mg three times daily
- Dental abscess: 3 gm, repeated after 10-12 hours
- Urinary tract infections: 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm
- Renal impairment: Dosage reduction may be necessary
- Reconstitution:
- Intramuscular: Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial
- Intravenous: Dissolve Amoxycillin 500 mg injection in 10 ml water for injection
Design elements
N/A
Usability features
- Oral administration
- Reconstituted suspension can be administered by adding to milk, fruit juice, or water
Interaction
- Concurrent use of Loxyl and Probenecid may result in increased and prolonged blood levels of Loxyl
- Loxyl may affect gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives
Contraindications
Penicillin hypersensitivity
Side effects
- Diarrhoea
- Indigestion
- Rash
- Pseudo-membranous colitis (rarely)
Pregnancy lactation
- Us fda pregnancy category: B
- Excretion in human milk: Yes
- Caution in lactating mothers: Caution should be exercised when Amoxicillin is administered to a lactating mother
Precautions warnings
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Loxyl should be discontinued and appropriate therapy should be instituted.
Therapeutic class
Broad spectrum penicillins
Storage conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.