Moxin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 70.00

Medicine Details

Category Details
Generic Amoxicillin trihydrate
Company Opsonin pharma ltd
Also available as
Moxin 500 mg capsule Moxin 250 mg tablet Moxin 875 mg tablet Moxin ds 250 mg suspension Moxin 125 mg pediatric drop Moxin 500 mg injection Moxin 250 mg injection

Indications

  • Ear, nose and throat infections
  • Lower respiratory tract infections
  • Skin and soft tissue infections
  • Genito-urinary tract infections
  • Venereal disease
  • Dental abscess treatment
  • H. pylori infection treatment
  • Duodenal ulcer disease treatment

Pharmacology

  • Broad spectrum penicillin
  • Effective against Gram-positive bacteria
  • Effective against Gram-negative bacteria
  • Inhibition of cell wall biosynthesis
  • Stable in the presence of gastric acid
  • Rapid absorption after oral administration
  • Widely distributed in body tissues and fluids

Dosage

  • Adult dosage: 250 mg three times daily
  • Adult dosage: 500 mg three times daily for severe infections
  • Children dosage: 125 mg three times daily
  • Children dosage: 250 mg three times daily for severe infections
  • Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
  • Otitis media dosage for adults: 1 g three times daily
  • Otitis media dosage for children: 40 mg/kg body weight daily in 3 divided doses (max. 3 g daily)
  • Pneumonia dosage: 500-1000 mg three times daily
  • Dental abscess dosage: 3 gm, repeated after 10-12 hours
  • Urinary tract infections dosage: 3 gm, repeated after 10-12 hours
  • Gonorrhoea dosage: Single dose of 2-3 gm with Probenecid 1 gm
  • Dosage adjustment in renal impairment

Administration

  • Reconstituted suspension can be administered by adding to milk, fruit juice, water
  • Immediate consumption of reconstituted suspension

Interaction

  • Concurrent use of Moxin and Probenecid may result in increased and prolonged blood levels of Moxin
  • Moxin may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral contraceptives

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Mild and transient side effects
  • Possible side effects: diarrhea, indigestion, rash
  • Rare occurrence of Pseudo-membranous colitis

Pregnancy & Lactation

  • US FDA pregnancy category: B
  • Use during pregnancy only if clearly needed
  • Excretion in human milk
  • Caution during lactation

Precautions & Warnings

  • Possibility of superinfections with mycotic and bacterial pathogens
  • Appropriate therapy for superinfections

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • Intramuscular reconstitution: Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial
  • Intravenous reconstitution: Dissolve Amoxycillin 500 mg injection in 10 ml water for injection

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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