Moxin DS 250 mg/5 ml (Powder for Suspension)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Opsonin pharma ltd |
| Also available as |
Title
Moxin DS
Categories
- Medicine
- Antibiotic
- Infection Treatment
Description
Moxin DS is an antibiotic indicated in the treatment of infections due to susceptible β-lactamase negative strains of microorganisms, including ear, nose and throat infections, lower respiratory tract infections, skin and soft tissue infections, genito-urinary tract infections, venereal disease, dental abscess, H.pylori infection, and duodenal ulcer disease. It is also used as a part of triple therapy.
Dosage
- Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
- Children: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
Pharmacology
Amoxicillin is a broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative bacteria. It inhibits the biosynthesis of cell wall and is stable in the presence of gastric acid. Peak plasma concentration is reached within 1 to 2 hours, and it is widely distributed in body tissues and fluids.
Administration
Reconstituted suspension can be administered by adding the required amount to milk, fruit juice, or water, and should then be taken immediately.
Interaction
Concurrent use of Moxin DS and Probenecid may result in increased and prolonged blood levels of Moxin DS. It may also affect gut flora and reduce the efficacy of combined oral estrogen/progesterone contraceptives.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side effects
Side effects are mild and transient, including diarrhea, indigestion, occasionally rash, and rarely pseudo-membranous colitis.
Pregnancy lactation
US FDA pregnancy category of Amoxicillin is B. Caution should be exercised when administered to a lactating mother.
Precautions warnings
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Moxin DS should be discontinued, and appropriate therapy should be instituted.
Therapeutic class
Broad spectrum penicillins
Reconstitution instructions
- Intramuscular: Add 2.5 ml water for injection to Amoxicillin 500 mg injection vial
- Intravenous: Dissolve Amoxicillin 500 mg injection in 10 ml water for injection
Storage conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.