Ampil 5 mg (Tablet)
Unit Price: ৳ 5.00 (50's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | The white horse pharmaceuticals ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Influences myocardial cells
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
Dosage & Administration
- Usual dose: 5 mg once daily for hypertension
- Maximum dose: 10 mg once daily for hypertension
- Lower dose for elderly and hepatic insufficiency
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration with Warfarin
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- No adequate and well-controlled studies in pregnant women
- Recommendation to discontinue nursing while using
Precautions & Warnings
- Hepatic impairment
- Pregnancy
- Breastfeeding
Use in Special Populations
- Dosage for children with hypertension
- Effect on blood pressure in children under 6 years
- Elderly tolerance
- No correlation with renal impairment
- Cautious dosage recommendation for hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Systemic hypotension
- Active cardiovascular support
- Elevation of extremities
- Vasoconstrictor use
- Intravenous calcium gluconate use
- Gastric lavage benefit
- Reduced absorption rate with charcoal
Therapeutic Class
Calcium-channel blockers
Storage Conditions
Store in a cool & dry place, protected from light