Ampre 5 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Kumudini pharma ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Calcium-channel blocker
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
Dosage & Administration
- Usual dose of 5 mg once daily
- Maximum dose of 10 mg once daily
- May be taken without regard to meals
Interaction
- Potential hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration with Warfarin
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant woman
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Recommendation to discontinue nursing while administered
Precautions & Warnings
- Hepatic impairment
- Pregnancy and breastfeeding
Use in Special Populations
- Dosage recommendations for children with hypertension
- Effect on blood pressure in patients under 6 years unknown
- Equally well tolerated by elderly and younger patients
- Normal dosage recommended for renal impairment
- Caution with dose selection for hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked and prolonged systemic hypotension
- Management through cardiovascular support
- Use of vasoconstrictor and intravenous calcium gluconate
- Gastric lavage and possibly charcoal use
- Dialysis unlikely to be beneficial
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Cool and dry place
- Protected from light