Pemox 125 mg/1.25 ml (Pediatric Drops)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Apc pharma ltd |
| Also available as |
Indications
- Ear, nose and throat infections
- Lower respiratory tract infections
- Skin and soft tissue infections
- Genito-urinary tract infections
- Venereal disease treatment
- Dental abscess therapy
- H. pylori infection treatment
Pharmacology
Amoxicillin is a broad spectrum penicillin effective against a wide range of bacteria. It inhibits the biosynthesis of the cell wall and is stable in gastric acid.
Dosage
- Adult: 250 mg three times daily, increasing up to 500 mg for severe infections
- Children: 125 mg three times daily, increasing up to 250 mg for severe infections
- Special Cases:
- Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
- Otitis media: 1 g three times daily for adult, 40 mg/kg daily in 3 divided doses for children (max. 3 g daily)
- Pneumonia: 500-1000 mg three times daily
- Dental abscess: 3 gm, repeated after 10-12 hours
- Urinary tract infections: 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm (Probenecid is contraindicated in children under 2 years)
- In renal impairment: may require total daily dosage reduction
Administration
Reconstituted suspension can be administered by adding to milk, fruit juice, or water, and should be taken immediately.
Interaction
Concurrent use of Pemox and Probenecid may lead to increased and prolonged blood levels of Pemox. Pemox may affect gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral contraceptives.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side Effects
- Diarrhoea
- Indigestion
- Rash
- Rarely pseudo-membranous colitis
Pregnancy & Lactation
Amoxicillin is classified as US FDA pregnancy category B. Caution should be exercised during lactation.
Precautions & Warnings
Superinfections with mycotic or bacterial pathogens should be kept in mind during therapy.
Therapeutic Class
Broad spectrum penicillins
Reconstitution
- Amoxycillin 500 mg Injection:
- Intramuscular: Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial
- Intravenous: Dissolve Amoxycillin 500 mg injection in 10 ml water for injection
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.