Pharmoxyl 500 mg (Capsule)

Unit Price: ৳ 5.86 (50's pack: ৳ 293.00)

Medicine Details

Category	Details
Generic	Amoxicillin trihydrate
Company	Pharmadesh laboratories ltd
Also available as	Pharmoxyl 250 mg capsule Pharmoxyl 125 mg suspension Pharmoxyl 125 mg pediatric drop

Indications

Ear, nose and throat infections
Lower respiratory tract infections
Skin and soft tissue infections
Genito-urinary tract infections
Venereal disease
Dental abscess
H. pylori infection

Pharmacology

Amoxicillin is a broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative bacteria. It inhibits cell wall biosynthesis and is rapidly absorbed after oral administration.

Dosage

Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
Children: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
Otitis media (adult): 1 g three times daily
Otitis media (children): 40 mg/kg body weight daily in 3 divided doses (max. 3 g daily)
Pneumonia: 500-1000 mg three times daily
Dental abscess: 3 gm, repeated after 10-12 hours
Urinary tract infections: 3 gm, repeated after 10-12 hours
Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm
In renal impairment: May require reduction of total daily dosage

Administration

Reconstituted suspension can be administered by adding the required amount to milk, fruit juice, or water.

Interaction

Concurrent use with Probenecid may result in increased and prolonged blood levels. Also, may affect gut flora and reduce efficacy of oral contraceptives.

Contraindications

Amoxicillin is contraindicated in penicillin hypersensitive patients.

Side Effects

Diarrhoea
Indigestion
Rash
Pseudo-membranous colitis (rare)

Pregnancy & Lactation

FDA pregnancy category B, caution should be exercised during lactation.

Precautions & Warnings

Possibility of superinfections with mycotic or bacterial pathogens should be kept in mind.

Therapeutic Class

Broad spectrum penicillins

Reconstitution

Intramuscular: Add 2.5 ml water for injection to 500 mg injection vial
Intravenous: Dissolve 500 mg injection in 10 ml water for injection

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.