Simox DS 250 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 65.25

Medicine Details

Indications

  • Ear infections
  • Nose infections
  • Throat infections
  • Respiratory tract infections
  • Lower respiratory tract infections
  • Skin and soft tissue infections
  • Genito-urinary tract infections
  • Venereal disease
  • Dental abscess
  • H. pylori infection
  • Duodenal ulcer disease

Pharmacology

  • Broad spectrum penicillin
  • Effective against Gram-positive and Gram-negative bacteria
  • Inhibition of cell wall biosynthesis
  • Stable in gastric acid
  • Rapid absorption after oral administration
  • Widely distributed in body tissues and fluids

Dosage

  • Adult dosage: 250 mg three times daily
  • Increased adult dosage for severe infections
  • Children dosage: 125 mg three times daily
  • Increased children dosage for severe infections
  • Specific dosages for purulent respiratory infection, otitis media, pneumonia, dental abscess, urinary tract infections, gonorrhoea, and renal impairment

Administration

Reconstituted suspension can be administered by adding to milk, fruit juice, or water, and should be taken immediately

Interaction

  • Concurrent use with Probenecid may increase and prolong blood levels
  • May affect gut flora leading to lower estrogen reabsorption and reduced efficacy of oral contraceptives

Contraindications

Contraindicated in penicillin hypersensitive patients

Side Effects

  • Mild and transient side effects including diarrhea, indigestion, and rash
  • Rare reports of pseudo-membranous colitis

Pregnancy & Lactation

US FDA pregnancy category B, caution needed during lactation

Precautions & Warnings

Possibility of superinfections with mycotic or bacterial pathogens should be kept in mind

Therapeutic Class

Broad spectrum penicillins

Reconstitution

Specific instructions for intramuscular and intravenous reconstitution of Amoxycillin 500 mg Injection

Storage Conditions

Keep in dry place away from light and heat, and out of the reach of children

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