CVnor 5 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications and Usage
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Influences myocardial cells
- Vascular smooth muscle effect
Dosage and Administration
- Usual dose of 5 mg once daily for hypertension
- Maximum dose of 10 mg once daily
- Lower dose for elderly and hepatic insufficiency
Drug Interactions
- Potential interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration with Warfarin
- No alteration by food
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy and Lactation
- Pregnancy Category C
- Potential benefit justifies potential risk to fetus
- Unknown excretion in human milk
- Nursing discontinuation recommended
Precautions and Warnings
- Hepatic impairment caution
- Pregnancy and breastfeeding caution
Special Populations
- Dosage for children with hypertension
- Effect in children under 6 years old unknown
- Normal dosage regimen for elderly
- Normal dosage for renal impairment
- Caution in hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Systemic hypotension
- Fatal outcome possible
- Active cardiovascular support required
- Vasoconstrictor may be helpful
- Intravenous calcium gluconate may be beneficial
- Gastric lavage may be worthwhile
- Administration of charcoal within 2 hours shown to reduce absorption
- Unlikely benefit from dialysis due to high protein binding
Therapeutic Class
Calcium-channel blockers
Storage Conditions
Store in a cool & dry place, protected from light