Tymox 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 30.20

Medicine Details

Indications

  • Treatment of ear, nose and throat infections
  • Treatment of lower respiratory tract infections
  • Treatment of skin and soft tissue infections
  • Treatment of genito-urinary tract infections
  • Treatment of venereal disease (e.g. acute uncomplicated gonorrhoea)
  • Treatment of dental abscess
  • Triple therapy for H. pylori infection and duodenal ulcer disease

Pharmacology

  • Broad spectrum penicillin
  • Effective against Gram-positive and Gram-negative bacteria
  • Inhibition of cell wall biosynthesis
  • Stable in the presence of gastric acid
  • Rapid absorption after oral administration
  • Widely distributed in body tissues and fluids

Dosage

  • Adult dosage: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
  • Children dosage: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
  • Specific dosages for severe or recurrent purulent respiratory infection, otitis media, pneumonia, dental abscess, urinary tract infections, and gonorrhoea
  • Adjustment needed for renal impairment

Administration

  • Reconstituted suspension administration with milk, fruit juice, or water

Interaction

  • Concurrent use of Tymox and Probenecid may result in increased and prolonged blood levels
  • Effect on gut flora leading to lower estrogen reabsorption and reduced efficacy of combined oral contraceptives

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Mild and transient side effects such as diarrhea, indigestion, rash
  • Rare cases of pseudo-membranous colitis reported

Pregnancy & Lactation

  • US FDA pregnancy category B
  • No adequate and well-controlled studies in pregnant women
  • Caution in lactating mothers due to excretion in human milk

Precautions & Warnings

  • Possible superinfections with mycotic or bacterial pathogens
  • Discontinue if superinfections occur and institute appropriate therapy

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • Intramuscular and intravenous reconstitution instructions for Amoxycillin 500 mg Injection

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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