Tymox 125 mg/1.25 ml (Pediatric Drops)

Indications

• Treatment of ear, nose and throat infections
• Treatment of lower respiratory tract infections
• Treatment of skin and soft tissue infections
• Treatment of genito-urinary tract infections
• Treatment of venereal disease (e.g. acute uncomplicated gonorrhoea)
• Treatment of dental abscess
• Triple therapy for H. pylori infection and duodenal ulcer disease

Pharmacology

• Broad spectrum penicillin
• Effective against Gram-positive and Gram-negative bacteria
• Inhibition of cell wall biosynthesis
• Stable in the presence of gastric acid
• Rapid absorption after oral administration
• Widely distributed in body tissues and fluids

Dosage

• Adult dosage: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
• Children dosage: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
• Specific dosages for severe or recurrent purulent respiratory infection, otitis media, pneumonia, dental abscess, urinary tract infections, and gonorrhoea
• Adjustment needed for renal impairment

Administration

• Reconstituted suspension administration with milk, fruit juice, or water

Interaction

• Concurrent use of Tymox and Probenecid may result in increased and prolonged blood levels
• Effect on gut flora leading to lower estrogen reabsorption and reduced efficacy of combined oral contraceptives

Contraindications

• Contraindicated in penicillin hypersensitive patients

Side Effects

• Mild and transient side effects such as diarrhea, indigestion, rash
• Rare cases of pseudo-membranous colitis reported

Pregnancy & Lactation

• US FDA pregnancy category B
• No adequate and well-controlled studies in pregnant women
• Caution in lactating mothers due to excretion in human milk

Precautions & Warnings

• Possible superinfections with mycotic or bacterial pathogens
• Discontinue if superinfections occur and institute appropriate therapy

Therapeutic Class

• Broad spectrum penicillins

Reconstitution

• Intramuscular and intravenous reconstitution instructions for Amoxycillin 500 mg Injection

Storage Conditions

• Keep in a dry place away from light and heat
• Keep out of the reach of children

Related Brands

• Tymox 125 mg/5 ml (Powder for Suspension) - somatec-pharmaceuticals-ltd
• Tymox 500 mg (Capsule) - somatec-pharmaceuticals-ltd
• Tycil 125 mg/1.25 ml (Pediatric Drops) - beximco-pharmaceuticals-ltd
• Tycil DS 250 mg/5 ml (Powder for Suspension) - beximco-pharmaceuticals-ltd
• Tycil 125 mg/5 ml (Powder for Suspension) - beximco-pharmaceuticals-ltd