Ultramox 500 mg (Capsule)

Unit Price: ৳ 7.50 (5 x 10: ৳ 375.00)

Strip Price: ৳ 75.00

Medicine Details

Category	Details
Generic	Amoxicillin trihydrate
Company	Globe pharmaceuticals ltd
Also available as	Ultramox 250 mg capsule Ultramox 125 mg suspension

Indications

Ear, nose and throat infections
Lower respiratory tract infections
Skin and soft tissue infections
Genito-urinary tract infections
Dental abscess therapy
H. pylori infection and duodenal ulcer therapy
Reduction of duodenal ulcer recurrence risk

Pharmacology

Broad spectrum penicillin, effective against Gram-positive and Gram-negative bacteria, acts through the inhibition of cell wall biosynthesis, stable in the presence of gastric acid, rapidly absorbed after oral administration, widely distributed in body tissues and fluids.

Dosage

Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
Children: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
Otitis media (adult): 1 g three times daily
Otitis media (children): 40 mg/kg body weight daily in 3 divided doses (max. 3 g daily)
Pneumonia: 500-1000 mg three times daily
Dental abscess: 3 gm, repeated after 10-12 hours
Urinary tract infections: 3 gm, repeated after 10-12 hours
Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm (Probenecid contraindicated in children under 2 years)
In renal impairment: may require reduction in total daily dosage

Administration

Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, or water, and should be taken immediately.

Interaction

Concurrent use with Probenecid may result in increased and prolonged blood levels of the medication. It may also affect gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.

Contraindications

Contraindicated in penicillin hypersensitive patients.

Side Effects

Diarrhoea
Indigestion
Rash
Rarely pseudo-membranous colitis

Pregnancy & Lactation

US FDA pregnancy category B, caution advised during lactation as the drug is excreted in human milk.

Precautions & Warnings

Consider the possibility of superinfections with mycotic or bacterial pathogens, and if they occur, discontinue Ultramox and initiate appropriate therapy.

Therapeutic Class

Broad spectrum penicillins

Reconstitution

Amoxycillin 500 mg Injection:
- Intramuscular: Add 2.5 ml water for injection to the vial
- Intravenous: Dissolve in 10 ml water for injection

Storage Conditions

Keep in a dry place away from light and heat, and out of the reach of children.