Cab 5 mg (Tablet)

Unit Price: ৳ 5.02 (5 x 10: ৳ 251.00)

Strip Price: ৳ 50.20

Medicine Details

Category	Details
Generic	Amlodipine besilate
Company	Aci limited

Indications

Essential hypertension
Angina pectoris
Vasospastic angina

Pharmacology

Amlodipine is a dihydropyridine calcium-channel blocker, with a long duration of action, used for the treatment of hypertension and angina pectoris.

Dosage & Administration

Usual dose is 5 mg once daily for hypertension
5 to 10 mg for angina
May be taken without regard to meals

Interaction

Potentially hazardous interactions: Combination of Cab and β-blockers should be avoided in patients with markedly impaired cardiac left ventricular function
Significant Interactions:
- Digoxin
- Cimetidine
- Warfarin
- Food

Contraindications

Hypersensitivity to dihydropyridine derivatives
Pregnant women

Side Effects

Dizziness
Flushing
Headache
Hypotension
Peripheral edema
Gastrointestinal disturbances
Increased micturition frequency
Lethargy
Eye pain
Mental depression
Rashes
Fever
Abnormalities in liver function

Pregnancy & Lactation

Pregnancy Category C. Amlodipine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Amlodipine is excreted in human milk. In the absence of this information, it is recommended that nursing be discontinued while Amlodipine is administered.

Precautions & Warnings

Precaution should be taken in patients with hepatic impairment and during pregnancy and breastfeeding.

Use in Special Populations

Children with hypertension from 6 years to 17 years of age
Children under 6 years old
Elderly
Renal impairment
Hepatic impairment

Overdose Effects

Symptoms: Excessive peripheral vasodilatation, reflex tachycardia, marked and prolonged systemic hypotension
Management: Active cardiovascular support, elevation of extremities, attention to fluid volume and urine output, vasoconstrictor use, intravenous calcium gluconate, gastric lavage, charcoal use, unlikelihood of benefit from dialysis