Xtramox 500 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Bengal drugs ltd |
| Also available as |
Indications
- Ear, nose and throat infections
- Lower respiratory tract infections
- Skin and soft tissue infections
- Genito-urinary tract infections
- Venereal disease
- Dental abscess
Pharmacology
Amoxicillin is a broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative bacteria.
Dosage
- Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
- Children: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
- Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
- Otitis media: 1 g three times daily for adult, 40 mg/kg body weight daily in 3 divided doses for children (max. 3 g daily)
- Pneumonia: 500-1000 mg three times daily
- Dental abscess: 3 gm, repeated after 10-12 hours
- Urinary tract infections: 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm
- Renal impairment: May be necessary to reduce the total daily dosage
Administration
Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, water.
Interaction
Concurrent use of Xtramox and Probenecid may result in increased and prolonged blood levels of Xtramox. Xtramox may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side Effects
- Diarrhoea
- Indigestion
- Rash
- Pseudo-membranous colitis
Pregnancy & Lactation
US FDA pregnancy category of Amoxicillin is B. Caution should be exercised when Amoxicillin is administered to a lactating mother.
Precautions & Warnings
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy.
Therapeutic Class
Broad spectrum penicillins
Reconstitution
- Intramuscular: Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial
- Intravenous: Dissolve Amoxycillin 500 mg injection in 10 ml water for injection
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.