Megacilin (4 gm+0.5 gm)/vial (IV Infusion)
4.5 gm vial: ৳ 1,004.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Piperacillin tazobactam |
| Company | Popular pharmaceuticals ltd |
Indications
- Intra-abdominal Infections
- Skin and Skin Structure Infections
- Female Pelvic Infections
- Community-acquired pneumonia
- Nosocomial pneumonia
Pharmacology
- Bactericidal activity
- Cell wall synthesis inhibition
- Beta-lactamase inhibitor
- Broad-spectrum antibiotic
Dosage & Administration
- Intravenous infusion
- Total daily dose for adults
- Initial presumptive treatment for nosocomial pneumonia
- Dosage for pediatric patients
Interaction
- Aminoglycosides
- Probenecid
- Anticoagulants
- Vecuronium
- Methotrexate
Contraindications
- History of allergic reactions to penicillins
- Cephalosporins
- Beta-lactamase inhibitors
Side Effects
- Adverse events involving skin and gastrointestinal system
- Immune hypersensitivity reactions
- Infections-Candidiasis and Pseudomembranous colitis
- Metabolism and nutrition disorders
- Respiratory disorders
- Vascular disorders
Pregnancy & Lactation
- Crosses placenta
- Insufficient data for pregnant women
- Excreted in human milk
Precautions & Warnings
- Serious hypersensitivity reactions
- Severe cutaneous adverse reactions
- Hematological effects
- Nephrotoxicity
- Clostridium difficile associated diarrhea
Use in Special Populations
- Pediatric Use
- Geriatric Use
- Renal Impairment
- Hepatic Impairment
- Patients with Cystic Fibrosis
Overdose Effects
- Neuromuscular excitability
- Convulsions
- Supportive and symptomatic treatment
Therapeutic Class
- Broad spectrum penicillins
- Other beta-lactam Antibiotics
Reconstitution
- Intravenous infusion over 30 minutes
- Withdrawal of diluent
- Reconstitution process
- Storage after reconstitution
Storage Conditions
- Temperature
- Light & moisture protection
- Keep out of reach of children