Tazopen (4 gm+0.5 gm)/vial (IV Infusion)

4.5 gm vial: ৳ 1,000.00

Medicine Details

Category Details
Generic Piperacillin tazobactam
Company Renata limited
Also available as

Indications

  • Treatment of moderate to severe infections
  • Intra-abdominal infections
  • Skin and skin structure infections
  • Female pelvic infections
  • Community-acquired pneumonia
  • Nosocomial pneumonia

Pharmacology

  • Bactericidal activity
  • Inhibition of septum and cell wall synthesis
  • Inhibition of beta-lactamases
  • Broad-spectrum antibiotic properties

Dosage & Administration

  • Intravenous infusion
  • Recommended total daily dose for adults
  • Recommended duration of treatment
  • Dosage for nosocomial pneumonia
  • Pediatric dosage based on age and weight
  • Dosage adjustment for renal impairment

Interaction

  • Aminoglycosides interaction
  • Probenecid interaction
  • Anticoagulants interaction
  • Vecuronium interaction
  • Methotrexate interaction

Contraindications

  • History of allergic reactions to penicillins or cephalosporins

Side Effects

  • Skin-related adverse events
  • Gastrointestinal adverse events
  • General disorders and administration site conditions
  • Immune hypersensitivity reactions
  • Infections
  • Metabolism and nutrition disorders
  • Musculoskeletal and connective tissue disorders
  • Psychiatric disorders
  • Vascular disorders
  • Respiratory, thoracic and mediastinal disorders

Pregnancy & Lactation

  • Placental transfer
  • Insufficient data on pregnancy risk
  • Excretion in human milk
  • Unknown effects on breastfed child

Precautions & Warnings

  • Serious hypersensitivity reactions
  • Severe cutaneous adverse reactions
  • Hematological effects
  • Nephrotoxicity
  • Clostridium difficile associated diarrhea

Use in Special Populations

  • Pediatric Use
  • Geriatric Use
  • Renal Impairment
  • Hepatic Impairment
  • Patients with Cystic Fibrosis

Overdose Effects

  • Neuromuscular excitability
  • Convulsions
  • Supportive and symptomatic treatment

Therapeutic Class

  • Broad spectrum penicillins
  • Other beta-lactam Antibiotics

Reconstitution

  • Intravenous infusion over 30 minutes
  • Reconstitution with 0.9% w/v Sodium Chloride solution
  • Vial usage and storage guidelines

Storage Conditions

  • Temperature and light/moisture considerations
  • Keep out of reach of children

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