Tazobac (4 gm+0.5 gm)/vial (IV Infusion)

4.5 gm vial: ৳ 1,003.00

Medicine Details

Category	Details
Generic	Piperacillin tazobactam
Company	Aci limited
Also available as	Tazobac 2 gm injection

Indications

Moderate to severe infections treatment
Intra-abdominal infections treatment
Skin and skin structure infections treatment
Female pelvic infections treatment
Community-acquired pneumonia treatment
Nosocomial pneumonia treatment

Pharmacology

Broad-spectrum bactericidal activity
Inhibition of septum and cell wall synthesis
Antibiotic spectrum enhancement
Beta-lactamase inhibition

Dosage & Administration

Administered by intravenous infusion
Dosage for adult patients
Dosage for nosocomial pneumonia
Dosage for pediatric patients
Dosage adjustment for renal impairment

Interaction

Aminoglycosides interaction
Probenecid interaction
Anticoagulants interaction
Vecuronium interaction
Methotrexate interaction

Contraindications

Allergic reactions to penicillins/cephalosporins

Side Effects

Skin rash
Gastrointestinal issues
Injection site reaction
Immune hypersensitivity reactions
Infections
Metabolism and nutrition disorders
Musculoskeletal disorders
Psychiatric disorders
Vascular disorders
Respiratory disorders

Pregnancy & Lactation

Crosses placenta
Insufficient data for pregnant women
Excretion in human milk
Effects on breastfed child

Precautions & Warnings

Serious hypersensitivity reactions
Severe cutaneous adverse reactions
Hematological effects
Nephrotoxicity
Clostridium difficile associated diarrhea

Use in Special Populations

Pediatric use
Geriatric use
Renal impairment
Hepatic impairment
Patients with cystic fibrosis

Overdose Effects

Nausea
Vomiting
Diarrhea
Neuromuscular excitability
Convulsions

Therapeutic Class

Broad spectrum penicillins
Other beta-lactam antibiotics

Reconstitution

Administration by intravenous infusion
Reconstitution process
Storage conditions after reconstitution

Storage Conditions

Temperature and light considerations
Keep out of reach of children

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