Calock 5 mg (Tablet)
Unit Price: ৳ 3.50 (50's pack: ৳ 175.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Medimet pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Vasodilation
- Increased coronary blood flow
- Myocardial oxygen supply
- Cardiac output
Dosage & Administration
- Usual dose 5 mg once daily for hypertension
- Usual dose 5-10 mg for angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No significant interactions with Digoxin
- No interaction with Cimetidine
- No significant alteration with Warfarin
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if potential benefit justifies potential risk to fetus
- Not known whether excreted in human milk
Precautions & Warnings
- Patients with hepatic impairment
- During pregnancy and breastfeeding
Use in Special Populations
- Dosing for children with hypertension
- Elderly patients
- Renal impairment
- Hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked hypotension
- Shock
- Management includes active cardiovascular support
- Intravenous calcium gluconate may be beneficial
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in cool & dry place protected from light