Calpin 5 mg (Tablet)
Unit Price: ৳ 4.50 (5 x 10: ৳ 225.00)
Strip Price: ৳ 45.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Globe pharmaceuticals ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
- Monotherapy
- Combination therapy
Pharmacology
- Calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
Dosage & Administration
- Usual dose of 5 mg once daily
- Maximum dose of 10 mg once daily
- Lower starting dose for elderly and hepatic insufficiency
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration to the effect of Warfarin
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use only if potential benefit justifies potential risk to the fetus
- Recommendation to discontinue nursing
Precautions & Warnings
- Hepatic impairment
- Pregnancy
- Breast feeding
Use in Special Populations
- Different dosing for children ages 6-17
- Effect on blood pressure in children under 6 unknown
- Elderly
- Renal impairment
- Hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked and prolonged systemic hypotension
- Shock
- Active cardiovascular support
- Monitoring of cardiac and respiratory function
- Elevation of extremities
- Attention to circulating fluid volume
- Urine output monitoring
- Vasoconstrictor usage
- Intravenous calcium gluconate
- Gastric lavage
- Charcoal usage
- Dialysis not likely to be beneficial
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool & dry place
- Protected from light