Abac 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 95.00

Medicine Details

Category Details
Generic Cephradine
Company Chemist laboratories ltd
Also available as
Abac 500 mg capsule Abac 125 mg pediatric drop

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms
  • Cell wall inhibition
  • Bactericidal action

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in cell wall of bacteria
  • Lysis of bacteria due to osmotic pressure

Dosage & Administration

  • Oral administration for adults
  • Oral administration for children
  • Injectable administration for adults
  • Injectable administration for children
  • Dosing based on infection type and severity
  • Dosage adjustment for renal or hepatic impairment

Interaction

  • Nephrotoxic drug interaction
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Safety not established in pregnancy
  • Excretion in breast milk
  • Caution in lactating mothers
  • Risk of dizziness

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Cross-sensitivity with penicillins
  • Positive result in Coombs testing
  • False positive urine glucose result
  • Lactose content
  • Dosage adjustment for renal impairment

Use in Special Populations

  • Recommended doses for renal impairment
  • Additional information for all patients
  • Caution in paediatric dosages

Overdose Effects

  • Non-specific symptoms
  • Nausea, vomiting, diarrhea
  • Supportive treatment
  • Gastric lavage if necessary

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Fresh preparation of suspension
  • Usage duration of reconstituted suspension
  • Usage duration of injection solutions
  • Storage temperature
  • Potency retention
  • Medicine storage safety

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