Adecef 500 mg (Capsule)

Unit Price: ৳ 12.50 (24's pack: ৳ 300.00)

Medicine Details

Category Details
Generic Cephradine
Company Supreme pharmaceutical ltd
Also available as
Adecef 125 mg suspension Adecef ds 250 mg suspension

Indications

  • Treatment of sensitive Gram-positive and Gram-negative bacterial infections
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptibility to specific microorganisms

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacterial cell wall
  • Cell lysis due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosing recommendations for urinary, respiratory, and skin infections
  • Special dosage considerations for elderly and patients with impaired renal or hepatic function

Interaction

  • Concomitant use with nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare adverse effects on blood, immune, psychiatric, nervous, hepatobiliary, renal, and urinary systems

Pregnancy & Lactation

  • Safety not established in pregnancy
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of superinfection with prolonged use
  • Cross-sensitivity with penicillins
  • Potential for false positive urine glucose results
  • Dosage adjustment in renal impairment
  • Lactose content caution for certain hereditary conditions

Use in Special Populations

  • Dosing recommendations for patients with renal impairment
  • Higher doses may be required for severe or chronic infections
  • Monitoring and treatment duration for specific infections

Overdose Effects

  • Non-specific symptoms including nausea, vomiting, and gastric upsets
  • Supportive treatment
  • Gastric lavage in case of large ingestion

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Fresh preparation for suspension
  • Reconstituted suspension usage timeframe
  • Injection solution usage timeframe
  • Potency retention at specific temperatures
  • Storage considerations
  • Dispensing only on prescription

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