Adecef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category	Details
Generic	Cephradine
Company	Supreme pharmaceutical ltd
Also available as	Adecef 500 mg capsule Adecef ds 250 mg suspension

Indications

Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
Upper respiratory tract infections
Lower respiratory tract infections
Urinary tract infections
Skin and soft tissue infections
Susceptibility to various microorganisms

Pharmacology

Semisynthetic broad spectrum bactericidal antibiotic
Active against gram-positive and gram-negative microorganisms
Inhibition of cell wall cross-linking process resulting in lysis of bacteria

Dosage & Administration

Oral administration for adults and children
Dosage adjustments for elderly and patients with impaired renal or hepatic function
Injectable administration dosages for adults and children

Interaction

Nephrotoxic drug interactions with increased risk of kidney damage
Enhanced renal toxicity with diuretics and probenecid

Contraindications

Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

Gastro-intestinal disturbances
Hypersensitivity phenomena
Skin reactions
Various rare side effects including glossitis, heartburn, dizziness, etc.
Blood, immune system, psychiatric, nervous system, hepatobiliary, renal, and urinary disorders potential side effects

Pregnancy & Lactation

Safety not established in pregnancy
Excretion in breast milk
Caution in lactating mothers
Warning about dizziness and operating hazardous machinery

Precautions & Warnings

Potential superinfection with prolonged use
Care with penicillin-hypersensitive patients
Coombs' testing caution
False positive urine glucose result possibility
Dosage adjustment in renal impairment
Contains lactose caution

Use in Special Populations

Recommended doses for renal impairment patients
Additional details for patients on haemodialysis
Higher doses for severe or chronic infections
Treatment duration recommendations
Bacteriological and clinical monitoring requirement

Overdose Effects

Non-specific symptoms including nausea, vomiting, diarrhea, and gastric upsets
Supportive treatment
Necessity of gastric lavage in case of large ingestion

Therapeutic Class

First generation Cephalosporins

Storage Conditions

Freshly prepared Adecef Suspension
Usage timeline for reconstituted Suspension
Usage timeline for Injection solutions
Potency retention at different temperatures
Variability in reconstituted solutions color
Dispensing only on prescription

Title

Adecef - Broad Spectrum Antibiotic

Description

Adecef is a broad spectrum bactericidal antibiotic indicated for various infections caused by susceptible bacteria. It inhibits cell wall cross-linking, leading to bacterial lysis. Dosage varies for different infections and patient populations. Caution is advised in special populations such as pregnant or lactating women and those with renal impairment. Side effects include gastro-intestinal disturbances and rare systemic reactions. Adecef belongs to the first generation Cephalosporins therapeutic class.