Ancef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 95.00

Medicine Details

Category Details
Generic Cephradine
Company Unimed unihealth pharmaceuticals ltd
Also available as
Ancef 250 mg capsule Ancef 500 mg capsule Ancef forte 250 mg suspension Ancef 125 mg pediatric drop

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacterial cell wall
  • Cell wall lysis due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment

Interaction

  • Nephrotoxic drug interaction
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity reactions
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen and other serum indicators

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Care with penicillin hypersensitivity
  • Positive result in Coombs’ testing
  • False positive urine glucose result
  • Lactose content warning for patients with specific intolerances

Use in Special Populations

  • Dosage recommendations for renal impairment
  • Higher doses required for chronic or severe infections
  • Regular monitoring for urinary tract infections
  • Transferring from injectable to oral treatment

Overdose Effects

  • Non-specific symptoms of overdose
  • Supportive treatment
  • Gastric lavage for large ingestions

Therapeutic Class

  • First generation cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Limited storage period for reconstituted suspension and injection solutions
  • Variation in color of reconstituted solutions
  • Dispensed on physician's prescription

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