Ancef 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 65.00

Medicine Details

Category Details
Generic Cephradine
Company Unimed unihealth pharmaceuticals ltd
Also available as
Ancef 250 mg capsule Ancef 500 mg capsule Ancef 125 mg suspension Ancef forte 250 mg suspension

Title

  • Ancef Antibiotic Medicine

Categories

  • Pharmaceuticals
  • Antibiotics
  • Medicine

Description

  • Ancef is a broad-spectrum bactericidal antibiotic used to treat infections caused by sensitive Gram-positive and Gram-negative bacteria.
  • Cephradine is the active ingredient with a main site of action on the cell wall of bacteria.

Indications

  • Treatment of upper respiratory tract infections like sinusitis, pharyngitis, and tonsillitis
  • Treatment of lower respiratory tract infections including bronchitis and pneumonia
  • Treatment of urinary tract infections like cystitis and pyelonephritis
  • Treatment of skin and soft tissue infections such as abscess and cellulitis

Pharmacology

  • Cephradine is a semisynthetic broad-spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in the cell wall of sensitive organisms resulting in lysis of bacteria

DosageAndAdministration

  • Oral administration for adults with urinary tract infections: 500mg four times daily or 1g twice daily
  • Injectable administration for adults: 2-4 gm daily in four equally divided doses up to 8 gm daily
  • Dosage adjustment necessary in renal impairment

Interaction

  • Concomitant use of nephrotoxic drugs may increase the risk of kidney damage
  • Diuretics and probenecid enhance the possibility of renal toxicity

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

SideEffects

  • Limited to gastrointestinal disturbances and hypersensitivity phenomena
  • Potential rare effects including blood disorders, immune system disorders, psychiatric disorders, and renal and urinary disorders

PregnancyAndLactation

  • Safety in pregnancy has not been established
  • Should be used with caution in lactating mothers
  • May cause dizziness, caution advised for operating hazardous machinery

PrecautionsAndWarnings

  • Prolonged use may result in the development of superinfection
  • Administer with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result when certain testing methods are used

UseInSpecialPopulations

  • Recommendations for patients with renal impairment
  • Higher doses may be required for chronic or severe infections

OverdoseEffects

  • Non-specific symptoms include nausea, vomiting, and gastric upsets
  • Treatment is mainly supportive

TherapeuticClass

  • First generation Cephalosporins

StorageConditions

  • Ancef Suspension should be freshly prepared
  • Reconstituted Suspension should be used within 7-14 days depending on storage temperature
  • Injection solutions retain potency for 2-12 hours based on storage conditions
  • Solutions may vary in color but potency is not affected

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