Avlosef 500 mg (Capsule)

Unit Price: ৳ 15.05 (8 x 4: ৳ 481.60)
Strip Price: ৳ 60.20

Medicine Details

Category Details
Generic Cephradine
Company Aci limited
Also available as
Avlosef 250 mg capsule Avlosef 125 mg pediatric drop Avlosef ds 250 mg suspension Avlosef 1 gm injection Avlosef 125 mg suspension

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms (in vitro)

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacterial cell wall
  • Lysis of bacteria due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults and children
  • Initial dose for injectable administration in adults and children
  • Maximum daily dosage
  • Dosage adjustment in renal impairment
  • Preparation and storage instructions

Interaction

  • Concomitant use with nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare side effects
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Investigations

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential for causing dizziness

Precautions & Warnings

  • Development of superinfection with prolonged use
  • Administration in patients hypersensitive to penicillins
  • Coombs’ testing
  • Potential for false positive urine glucose result
  • Lactose content

Use in Special Populations

  • Dosing recommendations for renal impairment
  • Dosing recommendations for patients on haemodialysis
  • Higher doses may be required for chronic or severe infections
  • Continuation of treatment post-symptom resolution
  • Regular bacteriological and clinical monitoring

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Necessity of gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension shelf life
  • Injection solutions shelf life
  • Variation in color of reconstituted solutions
  • Dispensing only on the prescription of a registered physician

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