Avlosef 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 95.29

Medicine Details

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptible microorganisms to Avlosef

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Activity against gram-positive and gram-negative microorganisms

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustments for renal impairment

Interaction

  • Increase in risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare adverse effects
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Investigations

Pregnancy & Lactation

  • Safety not established in pregnancy
  • Excretion in breast milk
  • Caution advised in lactating mothers

Precautions & Warnings

  • Development of superinfection with prolonged use
  • Risk of cross-sensitivity between beta-lactam antibiotics
  • Positive Coombs’ testing
  • False positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose

Use in Special Populations

  • Doses recommended for patients with renal impairment
  • Dosage recommendations for patients on haemodialysis
  • Additional information for all patients
  • Caution in paediatric dosages
  • Transfer from intramuscular/intravenous to oral treatment

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Gastric lavage if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Preparation and shelf life of Avlosef Suspension and Injection solutions
  • Potency retention at different temperatures
  • Dispensing on prescription only

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