Bactokil 250 mg (Capsule)

Unit Price: ৳ 6.50 (24's pack: ৳ 156.00)

Medicine Details

Category Details
Generic Cephradine
Company Virgo pharmaceuticals ltd
Also available as
Bactokil 500 mg capsule Bactokil 125 mg suspension

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in cell wall of bacteria

Dosage & Administration

  • Oral administration
  • Injectable administration
  • Dosage for adults and children
  • Maximum daily dosage
  • Dosage adjustment in renal impairment

Interaction

  • Concomitant use of nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Investigations

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Care with patients hypersensitive to penicillins
  • Positive result in Coombs' testing
  • Potential for false positive urine glucose result
  • Lactose content caution

Use in Special Populations

  • Doses for patients not on haemodialysis based on creatinine clearance
  • Doses for patients on chronic, intermittent haemodialysis
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required

Overdose Effects

  • Non-specific symptoms such as nausea and vomiting
  • Supportive treatment
  • Gastric lavage may be necessary

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Reconstituted Suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours at room temperature
  • Solutions retain potency for 12 hours when stored at 5°C
  • Dispensed only on prescription

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