Bactokil 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Virgo pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections: sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis, otitis media
- Lower respiratory tract infections: bronchitis, lobar pneumonia, bronchopneumonia
- Urinary tract infections: cystitis, urethritis, pyelonephritis
- Skin and soft tissue infections: abscess, cellulitis, furunculosis, impetigo
- Susceptible microorganisms: Staphylococci, Streptococci, Escherichia coli, Klebsiella spp, Proteus mirabilis, Haemophilus influenza, Shigella spp, Salmonella spp, Neisseria spp
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against gram-positive and gram-negative microorganisms
- Inhibits cross-linking process in bacterial cell wall
- Causes lysis of bacteria due to external osmotic pressure
Dosage & Administration
- Oral administration for adults: urinary tract infections, respiratory tract infections, skin and soft tissue infections
- Oral administration for children
- Maximum daily dosage: 4 gm
- Injectable administration for adults and children
- Dosage adjustment in renal impairment
Interaction
- Increased risk of kidney damage with concomitant use of nephrotoxic drugs
- Enhanced renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Glossitis
- Dizziness
- Nausea, vomiting, diarrhea, abdominal pain
- Vaginitis, candida overgrowth
- Joint pains, edema
- Blood disorders, immune system disorders, psychiatric disorders
- Liver and renal disorders
Pregnancy & Lactation
- No established safety in pregnancy
- Excretion in breast milk
- Caution in lactating mothers
Precautions & Warnings
- Prolonged use may result in superinfection
- Caution in patients hypersensitive to penicillins
- Positive result in Coombs’ testing
- Possible false positive urine glucose result
- Lactose content precaution for certain patients
Use in Special Populations
- Recommended doses for renal impairment
- Additional information for all patients regardless of age or weight
- Regular bacteriological and clinical monitoring
Overdose Effects
- Non-specific symptoms: nausea, vomiting, diarrhea, gastric upsets
- Supportive treatment
- Gastric lavage in case of large ingestion
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Bactokil Suspension should be freshly prepared
- Reconstituted Suspension usage timeframe
- Bactokil Injection solutions usage timeframe
- Storage temperature impact on solution potency
- Dispensed only on the prescription of a registered physician