Bactokil 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Virgo pharmaceuticals ltd
Also available as
Bactokil 250 mg capsule Bactokil 500 mg capsule

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections: sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis, otitis media
  • Lower respiratory tract infections: bronchitis, lobar pneumonia, bronchopneumonia
  • Urinary tract infections: cystitis, urethritis, pyelonephritis
  • Skin and soft tissue infections: abscess, cellulitis, furunculosis, impetigo
  • Susceptible microorganisms: Staphylococci, Streptococci, Escherichia coli, Klebsiella spp, Proteus mirabilis, Haemophilus influenza, Shigella spp, Salmonella spp, Neisseria spp

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacterial cell wall
  • Causes lysis of bacteria due to external osmotic pressure

Dosage & Administration

  • Oral administration for adults: urinary tract infections, respiratory tract infections, skin and soft tissue infections
  • Oral administration for children
  • Maximum daily dosage: 4 gm
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment

Interaction

  • Increased risk of kidney damage with concomitant use of nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Glossitis
  • Dizziness
  • Nausea, vomiting, diarrhea, abdominal pain
  • Vaginitis, candida overgrowth
  • Joint pains, edema
  • Blood disorders, immune system disorders, psychiatric disorders
  • Liver and renal disorders

Pregnancy & Lactation

  • No established safety in pregnancy
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Caution in patients hypersensitive to penicillins
  • Positive result in Coombs’ testing
  • Possible false positive urine glucose result
  • Lactose content precaution for certain patients

Use in Special Populations

  • Recommended doses for renal impairment
  • Additional information for all patients regardless of age or weight
  • Regular bacteriological and clinical monitoring

Overdose Effects

  • Non-specific symptoms: nausea, vomiting, diarrhea, gastric upsets
  • Supportive treatment
  • Gastric lavage in case of large ingestion

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Bactokil Suspension should be freshly prepared
  • Reconstituted Suspension usage timeframe
  • Bactokil Injection solutions usage timeframe
  • Storage temperature impact on solution potency
  • Dispensed only on the prescription of a registered physician

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