Belocef 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Amico laboratories ltd
Also available as
Belocef 250 mg capsule Belocef ds 250 mg suspension Belocef 125 mg pediatric drop

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections: sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis, otitis media
  • Lower respiratory tract infections: bronchitis, lobar pneumonia, bronchopneumonia
  • Urinary tract infections: cystitis, urethritis, pyelonephritis
  • Skin and soft tissue infections: abscess, cellulitis, furunculosis, impetigo

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacteria cell wall
  • Main site of action is the cell wall of bacteria

Dosage & Administration

  • Oral administration for adults: 500mg-1g dosage
  • Oral administration for children: 25-50mg/kg total daily dose
  • Injectable administration for adults: 2-4g daily dosage
  • Injectable administration for children: 50-100mg/kg daily dosage

Interaction

  • Concomitant use of nephrotoxic drugs may increase risk of kidney damage
  • Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare: Glossitis, heartburn, dizziness, nausea, vomiting, diarrhoea
  • Rare: Fever, anaemia, liver enzyme disturbances, interstitial nephritis

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk, caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in development of superinfection
  • Administer with care to patients hypersensitive to penicillins
  • May cause a positive result in Coombs’ testing

Use in Special Populations

  • Recommended doses for renal impairment
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required

Overdose Effects

  • Non-specific symptoms: nausea, vomiting, diarrhoea, gastric upsets

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours - 12 hours
  • Solutions may vary in color, but potency is retained

Related Brands