Betasef 500 mg (Capsule)

Unit Price: ৳ 15.00 (5 x 4: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Product Title and Categories

  • Betasef
  • Antibiotic
  • Medicine
  • First generation Cephalosporins

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections (sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis, otitis media)
  • Lower respiratory tract infections (bronchitis, lobar pneumonia, bronchopneumonia)
  • Urinary tract infections (cystitis, urethritis, pyelonephritis)
  • Skin and soft tissue infections (abscess, cellulitis, furunculosis, impetigo)

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacterial cell wall

Dosage and Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment
  • Maximum daily dosage: 4 gm

Interactions

  • Nephrotoxic drugs may increase the risk of kidney damage
  • Diuretics and probenecid enhance renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Glossitis, heartburn, dizziness, nausea, vomiting, diarrhoea, abdominal pain, vaginitis, candida overgrowth
  • Rare blood disorders, immune system disorders, psychiatric disorders, nervous system disorders, hepatobiliary disorders, renal and urinary disorders
  • Elevation of blood urea nitrogen, serum creatinine, liver enzymes

Pregnancy and Lactation

  • Teratogenicity not demonstrated in animal studies
  • Caution advised for lactating mothers
  • Patients cautioned about operating hazardous machinery

Precautions and Warnings

  • Prolonged use may result in superinfection
  • Care in patients hypersensitive to penicillins
  • Potential positive result in Coombs’ testing
  • May cause a false positive urine glucose result with certain testing methods
  • Dosage adjustment necessary in renal impairment
  • Contains lactose, not suitable for certain patients

Use in Special Populations

  • Recommended doses for patients with renal impairment and on haemodialysis
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring for urinary tract infections
  • Paediatric dosages should not exceed those specified for adults

Overdose Effects

  • Non-specific symptoms such as nausea, vomiting, diarrhoea, and gastric upsets
  • Supportive treatment advised
  • Gastric lavage may be necessary in case of large ingestion

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Suspension should be freshly prepared
  • Reconstituted Suspension should be used within designated timeframes
  • Injection solutions retain potency for specific durations
  • Do not use after the date of expiry
  • Keep out of reach of children
  • To be dispensed only on the prescription of a registered physician

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