Cefadin 500 mg (Capsule)

Unit Price: ৳ 12.00 (7 x 4: ৳ 336.00)

Strip Price: ৳ 48.00

Medicine Details

Category	Details
Generic	Cephradine
Company	Ziska pharmaceuticals ltd
Also available as	Cefadin 125 mg suspension

Indications

Treatment of upper respiratory tract infections
Treatment of lower respiratory tract infections
Treatment of urinary tract infections
Treatment of skin and soft tissue infections
Antibiotic for gram-positive bacteria
Antibiotic for gram-negative bacteria
Susceptible microorganisms
Sensitive to cephradine
Broad spectrum antibiotic

Pharmacology

Bactericidal action
Active against gram-positive microorganisms
Active against gram-negative microorganisms
Inhibition of cross-linking process in bacteria cell walls
Cell wall lysis due to external osmotic pressure

Dosage & Administration

Dosage for oral administration in adults
Dosage for oral administration in children
Maximum daily dosage
Dosage for injectable administration in adults
Dosage for injectable administration in children
Dosage in elderly patients
Monitoring in patients with impaired renal or hepatic function

Interaction

Risk of kidney damage with nephrotoxic drugs
Enhanced renal toxicity with diuretics and probenecid

Contraindications

Hypersensitivity to cephalosporins

Side Effects

Gastro-intestinal disturbances
Hypersensitivity reactions
Skin reactions
Glossitis
Heartburn
Dizziness
Nausea
Vomiting
Diarrhoea
Abdominal pain
Vaginitis
Candida overgrowth
Blood disorders
Fever
Anaphylaxis
Psychiatric disorders
Hepatobiliary disorders
Renal and urinary disorders
Elevation of blood urea nitrogen
Elevation of serum creatinine
Elevation of liver enzymes
Investigations on blood and liver function

Pregnancy & Lactation

Safety in pregnancy not established
Excretion in breast milk
Precautions for lactating mothers

Precautions & Warnings

Risk of superinfection
Care in patients hypersensitive to penicillins
Positive result in Coombs' testing
False positive urine glucose result
Dosage adjustment in renal impairment
Lactose content

Use in Special Populations

Doses for patients with renal impairment
Doses for patients on haemodialysis
Higher doses for chronic or severe infections
Continued treatment for certain infections
Monitoring for urinary tract infections

Overdose Effects

Non-specific symptoms
Supportive treatment
Gastric lavage if large amount ingested

Therapeutic Class

First generation cephalosporins

Storage Conditions

Shelf life of reconstituted suspension
Usage timeframe for injection solutions
Potency retention with refrigeration
Variation of color in reconstituted solutions
Dispensing under physician's prescription

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