Ceflin 500 mg (Capsule)
Unit Price: ৳ 12.66 (20's pack: ৳ 253.20)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Nipa pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against both gram-positive and gram-negative microorganisms
- Inhibits cross-linking process in bacterial cell walls
- Cell lysis due to external osmotic pressure
Dosage & Administration
- For oral and injectable administration
- Dosage varies for adults, children, and elderly
- Maximum daily dosage
- Dose adjustment for renal impairment
Interaction
- Concomitant use of nephrotoxic drugs may increase risk of kidney damage
- Diuretics and probenecid enhance possibility of renal toxicity
Contraindications
- Not to be used in patients with known or suspected hypersensitivity to cephalosporins
Side Effects
- Limited to gastro-intestinal disturbances and hypersensitivity phenomena
- Possible skin reactions
- Rare side effects like glossitis, heartburn, dizziness, nausea, etc.
- Rare blood, immune system, psychiatric, nervous system, hepatobiliary, renal and urinary disorders
Pregnancy & Lactation
- Safety in pregnancy not established
- Caution advised in lactating mothers
- Patients cautioned about operating hazardous machinery
Precautions & Warnings
- Prolonged use may result in superinfection
- Caution with patients hypersensitive to penicillins
- Cephalosporin antibiotics may cause a positive result in Coombs’ testing
- May cause a false positive urine glucose result with certain tests
- Contains lactose, not suitable for certain patients
Use in Special Populations
- Dosing recommendations for renal impairment and haemodialysis patients
- Higher doses may be required for chronic or severe infections
- Paediatric dosages should not exceed those for adults
Overdose Effects
- Non-specific symptoms like nausea, vomiting, diarrhoea and gastric upsets
- Supportive treatment, gastric lavage if necessary
Therapeutic Class
- First generation Cephalosporins
Storage Conditions
- Freshly prepared suspension, to be used within specified timeframes
- Injection solutions retain potency for limited duration
- Keep out of reach of children, dispensed only on prescription