Ceflin 500 mg (Capsule)

Unit Price: ৳ 12.66 (20's pack: ৳ 253.20)

Medicine Details

Category Details
Generic Cephradine
Company Nipa pharmaceuticals ltd
Also available as
Ceflin 125 mg suspension

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacterial cell walls
  • Cell lysis due to external osmotic pressure

Dosage & Administration

  • For oral and injectable administration
  • Dosage varies for adults, children, and elderly
  • Maximum daily dosage
  • Dose adjustment for renal impairment

Interaction

  • Concomitant use of nephrotoxic drugs may increase risk of kidney damage
  • Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Limited to gastro-intestinal disturbances and hypersensitivity phenomena
  • Possible skin reactions
  • Rare side effects like glossitis, heartburn, dizziness, nausea, etc.
  • Rare blood, immune system, psychiatric, nervous system, hepatobiliary, renal and urinary disorders

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Caution advised in lactating mothers
  • Patients cautioned about operating hazardous machinery

Precautions & Warnings

  • Prolonged use may result in superinfection
  • Caution with patients hypersensitive to penicillins
  • Cephalosporin antibiotics may cause a positive result in Coombs’ testing
  • May cause a false positive urine glucose result with certain tests
  • Contains lactose, not suitable for certain patients

Use in Special Populations

  • Dosing recommendations for renal impairment and haemodialysis patients
  • Higher doses may be required for chronic or severe infections
  • Paediatric dosages should not exceed those for adults

Overdose Effects

  • Non-specific symptoms like nausea, vomiting, diarrhoea and gastric upsets
  • Supportive treatment, gastric lavage if necessary

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension, to be used within specified timeframes
  • Injection solutions retain potency for limited duration
  • Keep out of reach of children, dispensed only on prescription

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