Ceflin 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 80.00

Medicine Details

Category Details
Generic Cephradine
Company Nipa pharmaceuticals ltd
Also available as
Ceflin 500 mg capsule

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections: sinusitis, pharyngitis, tonsillitis, laryngo-tracheo bronchitis, otitis media
  • Lower respiratory tract infections: bronchitis (acute and chronic), lobar pneumonia, bronchopneumonia
  • Urinary tract infections: cystitis, urethritis, pyelonephritis
  • Skin and soft tissue infections: abscess, cellulitis, furunculosis, impetigo

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in the cell wall of bacteria

Dosage & Administration

  • Oral administration for adults, children, and elderly
  • Injectable administration for adults and children
  • Dosage adjustment necessary in renal impairment

Interaction

  • Concomitant use with nephrotoxic drugs may increase risk of kidney damage
  • Diuretics and probenecid enhance possibility of renal toxicity

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare: glossitis, heartburn, dizziness, tightness in the chest, nausea, vomiting, diarrhea, abdominal pain, vaginitis, candida overgrowth, urticaria, skin rashes, joint pains, edema

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk, caution in lactating mothers

Precautions & Warnings

  • Prolonged use may result in the development of superinfection
  • Administer with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result

Use in Special Populations

  • Renal impairment dosing recommendations for patients on haemodialysis
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required

Overdose Effects

  • Non-specific symptoms: nausea, vomiting, diarrhea, gastric upsets
  • Supportive treatment, gastric lavage if large amount ingested

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Suspension should be freshly prepared
  • Reconstituted Suspension should be used within 7-14 days
  • Injection solutions should be used within 2 hours at room temperature
  • Solutions retain potency for 12 hours at 5°C
  • Keep out of the reach of children

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