Ceframed 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 50.00

Medicine Details

Category Details
Generic Cephradine
Company Medimet pharmaceuticals ltd
Also available as
Ceframed 250 mg capsule Ceframed 500 mg capsule Ceframed 125 mg suspension

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Susceptible microorganisms
  • Semisynthetic broad spectrum bactericidal antibiotic

Pharmacology

  • Bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process
  • Lysis of bacteria due to external osmotic pressure

Dosage & Administration

  • Dosage for adults (urinary tract infections)
  • Dosage for adults (respiratory tract infections)
  • Dosage for adults (skin and soft tissue infections)
  • Dosage for children
  • Dosage for elderly
  • Dosage for injectable administration in adults
  • Dosage for injectable administration in children

Interaction

  • Nephrotoxic drug interaction
  • Enhanced risk of renal toxicity

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Development of superinfection
  • Cross-sensitivity between beta-lactam antibiotics
  • Positive result in Coombs' testing
  • False positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose

Use in Special Populations

  • Renal impairment dosages
  • Haemodialysis dosages
  • Recommendations for all patients
  • Monitoring required for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms
  • Nausea
  • Vomiting
  • Diarrhoea
  • Gastric upsets

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Reconstituted suspension shelf life
  • Injection solution shelf life
  • Storage temperature impact on potency
  • Variability in reconstituted solution color

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