Cefranov 500 mg (Capsule)
Unit Price: ৳ 12.50 (24's pack: ৳ 300.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Novus pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
- Upper respiratory tract infections
- Lower respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
Pharmacology
- Broad spectrum bactericidal antibiotic
- Active against both gram-positive and gram-negative microorganisms
- Inhibits cross-linking process of cell wall of bacteria
- Cell lysis due to external osmotic pressure
Dosage & Administration
- Oral administration for adults and children
- Injectable administration for adults and children
- Dosage adjustment in renal impairment
- Maximum daily dosage of 4 gm
Interaction
- Increased risk of kidney damage with concomitant use of nephrotoxic drugs
- Enhanced renal toxicity with diuretics and probenecid
Contraindications
- Hypersensitivity to cephalosporins
Side Effects
- Gastro-intestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Blood disorders
- Fever and serum sickness like reactions
- Abdominal pain
- Liver enzyme disturbances
- Reversible interstitial nephritis
Pregnancy & Lactation
- Caution in lactating mothers
- Excretion in breast milk
- Safety in pregnancy not established
- Potential dizziness
Precautions & Warnings
- Possible superinfection due to prolonged use
- Risk of cross-sensitivity between beta-lactam antibiotics
- Positive Coombs’ test result
- False positive urine glucose result
- Lactose content precautions
Use in Special Populations
- Recommended doses for renal impairment and haemodialysis
- Higher doses for chronic or severe infections
- Continued treatment for persistent infections
Overdose Effects
- Non-specific symptoms such as nausea, vomiting, diarrhoea
- Supportive treatment
- Gastric lavage if necessary
Therapeutic Class
- First generation cephalosporins
Storage Conditions
- Fresh preparation of Suspension
- Reconstituted Suspension use within 7-14 days
- Injection solutions use within 2 hours at room temperature
- Solutions retain potency for 12 hours at 5°C
- Variations in color of reconstituted solutions
- Dispensing only on prescription of a registered physician