Cephid 250 mg (Capsule)
Unit Price: ৳ 6.52 (6 x 5: ৳ 195.60)
Strip Price: ৳ 32.60
Medicine Details
| Category | Details |
|---|---|
| Generic | Cephradine |
| Company | Zenith pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of upper respiratory tract infections
- Treatment of lower respiratory tract infections
- Treatment of urinary tract infections
- Treatment of skin and soft tissue infections
Pharmacology
- Semisynthetic broad spectrum bactericidal antibiotic
- Active against both gram-positive and gram-negative microorganisms
- Inhibits cross-linking process in cell wall of bacteria
Dosage & Administration
- For oral administration - Adults:
- Urinary tract infections: 500mg four times daily or 1g twice daily
- Respiratory tract infections: 250 to 500mg four times daily or 500mg to 1g twice daily
- Skin and soft tissue infections: 250 to 500mg four times daily or 500mg to 1g twice daily
- For oral administration - Children:
- Total daily dose of 25 to 50mg/kg given in two or four equally divided doses
- Otitis media: Total daily dose of 75 to 100mg/kg given in divided doses 6 to 12 hourly
- For injectable administration - Adult: 2-4 gm daily in four equally divided doses up to 8 gm daily
- For injectable administration - Children: 50-100 mg/kg daily in four equally divided doses, up to 300 mg/kg daily in severe infection
Interaction
- Concomitant use of nephrotoxic drugs may increase the risk of kidney damage
- Diuretics and probenecid enhanced possibility of renal toxicity
Contraindications
Hypersensitivity to cephalosporins
Side Effects
- Gastrointestinal disturbances
- Hypersensitivity phenomena
- Skin reactions
- Hypertonia
- Dizziness
- Nervousness
- Liver enzyme disturbances
- Reversible interstitial nephritis
Pregnancy & Lactation
Safety in pregnancy not established, excreted in breast milk, caution in lactating mothers
Precautions & Warnings
- Prolonged use may result in the development of superinfection
- Administered with care to patients hypersensitive to penicillins
- May cause a false positive urine glucose result
- Dosage adjustment necessary in renal impairment
- Contains lactose, not recommended for patients with certain hereditary problems
Use in Special Populations
- Dosing recommendations for patients with renal impairment
- Higher doses may be required for chronic or severe infections
- Regular bacteriological and clinical monitoring required
Overdose Effects
Non-specific symptoms like nausea, vomiting, and diarrhoea
Therapeutic Class
First generation Cephalosporins
Storage Conditions
- Cephid Suspension should be freshly prepared
- Reconstituted Suspension should be used within 7 to 14 days
- Cephid Injection solutions should be used within 2 hours when kept at room temperature