Diplor 5 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
Dosage & Administration
- Usual dose: 5 mg once daily
- Maximum dose: 10 mg once daily
- Lower dose for elderly and hepatic insufficiency
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration of Warfarin effect
- Absence of food interaction
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy justified by benefit-risk assessment
- Recommendation to discontinue nursing during administration
Precautions & Warnings
- Precaution in hepatic impairment
- Precaution during pregnancy and breastfeeding
Use in Special Populations
- Different dosage for children and elderly
- Normal dosage in renal impairment
- Caution in mild to moderate hepatic impairment
- Initiation at lower dose in severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked systemic hypotension up to shock
- Clinically significant hypotension management
- Active cardiovascular support
- Elevation of extremities
- Attention to fluid volume and urine output
- Potential benefit of vasoconstrictor
- Potential benefit of calcium gluconate
- Potential benefit of gastric lavage
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in cool, dry place
- Protect from light