Cephradex 500 mg (Capsule)

Unit Price: ৳ 12.50 (20's pack: ৳ 250.00)

Medicine Details

Category Details
Generic Cephradine
Company Marker pharma ltd
Also available as
Cephradex ds 125 mg suspension

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Semi-synthetic broad-spectrum bactericidal antibiotic
  • Activeness against both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacteria cell walls
  • Bacterial lysis due to external osmotic pressure

Dosage & Administration

  • Oral Administration:
    • Adults:
      • Treatment dosage for urinary tract infections
      • Treatment dosage for respiratory tract infections
      • Treatment dosage for skin and soft tissue infections
    • Children:
      • Total daily dose for different types of infections
      • Maximum daily dosage
  • Injectable Administration:
    • Adults:
      • Usual dose
      • Prophylactic dose
    • Children:
      • Dose for severe infection

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Common:
    • Gastrointestinal disturbances
  • Occasional:
    • Hypersensitivity reactions
    • Skin reactions
    • Glossitis
    • Heartburn
    • Dizziness
    • Nausea
    • Vomiting
    • Diarrhea
    • Abdominal pain
  • Rare:
    • Joint pains
    • Edema
    • Blood disorders
    • Immune system disorders
    • Psychiatric disorders
    • Nervous system disorders
    • Hepatobiliary disorders
    • Renal and urinary disorders
    • Elevation of blood urea nitrogen

Pregnancy & Lactation

  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential for dizziness

Precautions & Warnings

  • General:
    • Risk of superinfection with prolonged use
    • Care with penicillin hypersensitivity
    • False positive urine glucose result
  • Renal Impairment:
    • Recommended doses for patients not on haemodialysis
    • Recommendations for patients on chronic, intermittent haemodialysis

Use in Special Populations

  • Dosing recommendations for patients with renal impairment
  • Higher doses for chronic or severe infections
  • Monitoring required for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Possible need for gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Freshly prepared suspension
  • Usage period for reconstituted suspension
  • Usage period for injection solutions
  • Storage temperature and potency retention
  • Dispensing on physician's prescription only

Related Brands