Cephran 125 mg/1.25 ml (Pediatric Drops)

15 ml bottle: ৳ 65.00

Medicine Details

Category Details
Generic Cephradine
Company Opsonin pharma ltd
Also available as
Cephran 500 mg capsule Cephran 125 mg suspension Cephran ds 250 mg suspension Cephran 500 mg injection Cephran 1 gm injection

Indications

  • Treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria
  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections

Pharmacology

  • Bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process of bacteria cell wall

Dosage & Administration

  • Oral administration for adults
  • Oral administration for children
  • Injectable administration for adults
  • Injectable administration for children
  • Dosage adjustments in renal impairment

Interaction

  • Concomitant use of nephrotoxic drugs
  • Enhanced risk of renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen
  • Elevation of serum creatinine

Pregnancy & Lactation

  • Uncertain safety in pregnancy
  • Excretion in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Potential for superinfection
  • Cross-sensitivity between beta-lactam antibiotics
  • Effect on Coombs’ testing
  • Potential for false positive urine glucose result
  • Lactose content

Use in Special Populations

  • Recommended doses for renal impairment
  • Higher doses may be required for chronic or severe infections

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Gastric lavage if necessary

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Preparation of suspension
  • Storage duration for reconstituted suspension
  • Storage duration for injection solutions
  • Medicine expiration date
  • Safety precaution for children

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