Diplor 10 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Influences myocardial cells
- Vasodilation
- Coronary blood flow increase
Dosage & Administration
- Usual dose is 5 mg once daily
- Maximum dose is 10 mg once daily
- Dose for elderly with hepatic insufficiency: 2.5 mg once daily
- Administered without regard to meals
Interaction
- Potential interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- Diplor did not significantly alter the effect of Warfarin
- Food does not alter the rate or extent of absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if benefit justifies risk
- Recommended to discontinue nursing while administered
Precautions & Warnings
- Caution in patients with hepatic impairment
- Caution during pregnancy and breastfeeding
Use in Special Populations
- Dosage for children with hypertension (6-17 years)
- Effect on blood pressure in children under 6 years not known
- Elderly tolerance
- Normal dosage recommended in renal impairment
- Caution in hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked systemic hypotension
- Shock with fatal outcome reported
- Active cardiovascular support needed
- Vasoconstrictor may be helpful
- Intravenous calcium gluconate beneficial
- Gastric lavage may be worthwhile
- No likely benefit from dialysis
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Cool & dry place
- Protected from light