Cephran 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 54.20 (1 x 4: ৳ 216.80)

Medicine Details

Category Details
Generic Cephradine
Company Opsonin pharma ltd
Also available as
Cephran 500 mg capsule Cephran 125 mg suspension Cephran ds 250 mg suspension Cephran 125 mg pediatric drop Cephran 1 gm injection

Title

  • Cephran

Categories

  • Medicine
  • Antibiotic
  • Pharmaceutical

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacterial cell wall

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential for causing dizziness

Precautions & Warnings

  • Risk of developing superinfection
  • Careful administration to penicillin-hypersensitive patients
  • Potential positive result in Coombs’ testing
  • Potential false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Additional dosage information for all patients
  • Caution in paediatric dosages

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Necessity of gastric lavage in case of large ingestions

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Fresh preparation of Cephran Suspension
  • Limited shelf life of reconstituted Suspension
  • Shelf life of Injection solutions
  • Variation in color of reconstituted solutions
  • Dispensing on prescription only

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