Cephran 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 54.20 (1 x 4: ৳ 216.80)

Medicine Details

Category Details
Generic Cephradine
Company Opsonin pharma ltd
Also available asCephran 500 mg capsuleCephran 125 mg suspensionCephran ds 250 mg suspensionCephran 125 mg pediatric dropCephran 1 gm injection

Title

  • Cephran

Categories

  • Medicine
  • Antibiotic
  • Pharmaceutical

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibits cross-linking process in bacterial cell wall

Dosage & Administration

  • Oral administration for adults and children
  • Injectable administration for adults and children
  • Dosage adjustment in renal impairment

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders

Pregnancy & Lactation

  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential for causing dizziness

Precautions & Warnings

  • Risk of developing superinfection
  • Careful administration to penicillin-hypersensitive patients
  • Potential positive result in Coombs’ testing
  • Potential false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Additional dosage information for all patients
  • Caution in paediatric dosages

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Necessity of gastric lavage in case of large ingestions

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Fresh preparation of Cephran Suspension
  • Limited shelf life of reconstituted Suspension
  • Shelf life of Injection solutions
  • Variation in color of reconstituted solutions
  • Dispensing on prescription only

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