Cephran 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 80.30

Medicine Details

Category Details
Generic Cephradine
Company Opsonin pharma ltd
Also available as
Cephran 500 mg capsule Cephran 125 mg suspension Cephran ds 250 mg suspension Cephran 125 mg pediatric drop Cephran 500 mg injection

Indications

  • Upper respiratory tract infections
  • Lower respiratory tract infections
  • Urinary tract infections
  • Skin and soft tissue infections
  • Gram-positive bacteria susceptibility
  • Gram-negative bacteria susceptibility

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in bacterial cell wall

Dosage & Administration

  • Recommended oral dosage for adults
  • Recommended oral dosage for children
  • Dosage for urinary tract infections
  • Dosage for respiratory tract infections
  • Dosage for skin and soft tissue infections
  • Maximum daily dosage
  • Dosage for injectable administration in adults
  • Dosage for injectable administration in children
  • Dosage adjustment for elderly and patients with impaired renal or hepatic function

Interaction

  • Nephrotoxic drug interaction
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastro-intestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of blood urea nitrogen and serum creatinine

Pregnancy & Lactation

  • Teratogenicity in animal studies
  • Excretion in breast milk
  • Caution in lactating mothers
  • Potential for causing dizziness

Precautions & Warnings

  • Prolonged use leading to superinfection
  • Risk of cross-sensitivity between beta-lactam antibiotics
  • Positive result in Coombs’ testing
  • Potential for causing false positive urine glucose result
  • Dosage adjustment for renal impairment
  • Lactose content precautions

Use in Special Populations

  • Recommended doses for renal impairment
  • Treatment duration for persistent infections

Overdose Effects

  • Non-specific symptoms
  • Supportive treatment
  • Necessity of gastric lavage

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Preparation and shelf life of suspension
  • Shelf life of injection solutions
  • Storage temperature effects on solution potency
  • Dispensing regulations

Related Brands