Ceproval 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 70.00

Medicine Details

Category Details
Generic Cephradine
Company Peoples pharma ltd
Also available as

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptible microorganisms: Staphylococci, Streptococci, E. coli, Klebsiella spp, Proteus mirabilis, Haemophilus influenza, Shigella spp, Salmonella spp, Neisseria spp

Pharmacology

  • Semisynthetic broad spectrum bactericidal antibiotic
  • Active against both gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in cell wall of bacteria

Dosage & Administration

  • Recommended dosage for adults and children
  • Oral administration dosage for urinary tract infections, respiratory tract infections, and skin infections
  • Injectable administration dosage for adults and children
  • Dosage adjustment for elderly and patients with impaired renal or hepatic function

Interaction

  • Increased risk of kidney damage when used with nephrotoxic drugs
  • Enhanced possibility of renal toxicity with diuretics and probenecid

Contraindications

  • Not to be used in patients with known or suspected hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Skin reactions
  • Rare effects including glossitis, heartburn, dizziness, nausea, vomiting, diarrhoea, abdominal pain, vaginitis, candida overgrowth, urticaria, skin rashes, joint pains, oedema

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Excreted in breast milk
  • Caution advised in lactating mothers

Precautions & Warnings

  • Prolonged use may result in the development of superinfection
  • Administer with care to patients hypersensitive to penicillins
  • May cause false positive urine glucose result
  • Dosage adjustment necessary in renal impairment
  • Contains lactose, caution in patients with rare hereditary problems

Use in Special Populations

  • Recommended doses for patients with renal impairment and on haemodialysis
  • Higher doses may be required for chronic or severe infections
  • Regular bacteriological and clinical monitoring required for chronic urinary tract infections

Overdose Effects

  • Non-specific symptoms including nausea, vomiting, and diarrhoea
  • Supportive treatment required

Therapeutic Class

  • First generation Cephalosporins

Storage Conditions

  • Suspension should be freshly prepared
  • Reconstituted Suspension should be used within 7-14 days
  • Injection solutions should be used within 2-12 hours
  • Stored medicines out of reach of children
  • To be dispensed only on prescription of a registered physician

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